One-dimensional modeling of microvascular hemodynamics in the retina using multimodal imaging

Modeling techniques are an essential complement to clinical studies of the retina, as they provide access non-measurable parameters throughout network and enable simulation controlled disturbances or pathologies. In this work, we propose development a patient-specific one-dimensional model arterial circulation in retina. Our is based on conservation laws utilizes morphometric velocimetric data obtained through multimodal imaging construct topology impose realistic boundary conditions. Specifically, our simulates blood flow from central retina artery terminal smallest arterioles. To validate model, perform sensitivity analysis compare its results published data. Finally, use investigate hemodynamic consequences focal stenosis retinal arteries. Overall, provides valuable tool for exploring complex dynamics their potential implications.